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Topical preparations (ointments and creams) are often applied to insect bites but are not very effective as the antihistamine chemical does not penetrate the skin well.Sedating antihistamines should not be used in children under the age of 2 years for any reason and should not be used in children under 6 years for cough and cold symptoms.Topical antihistamine creams, present in many forms of over-the-counter anti-itch creams, should not be used for the treatment of hives or other skin allergies.

difference between sedating and non sedating antihistamines-11

It is usual to classify H1-antihistamines into two classes: old ones, called first-generation agents, which are sedating and recent ones, called second-generation agents which have slight or no sedating effects because they do not cross the blood-brain barrier.

As well as tablets, antihistamines are available as injections, elixirs, and creams.

An injection can be given in case of severe allergic reaction (although in such cases, adrenaline (epinephrine) may be more appropriate and can be life-saving).

Antihistamines work by blocking the effects of a chemical called histamine that is responsible for many allergic symptoms.

Patients who experience significant allergic symptoms regularly may take daily antihistamines to keep their symptoms under control.

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